High initial burst release of gentamicin formulated as PLGA microspheres implant for treating orthopaedic infection

Antibiotic treatment of orthopaedic infection is complicated by systemic toxicity and the need of effective therapeutic concentration necessary to ensure optimum killing of bacteria. To overcome the problem of systemic toxicity and to achieve a high initial release followed by sustained release of a...

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Main Authors: Harun Ismail, Ahmad Fahmi, Doolaanea, Abd Monem, Awang, Mohamed, Mohamed, Farahidah
格式: Article
语言:English
出版: Academic Sciences 2012
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在线阅读:http://irep.iium.edu.my/25825/1/High_burst_release_gentamicin_formulated_as_PLGAmicrospheres.pdf
http://irep.iium.edu.my/25825/
http://www.ijppsjournal.com/Vol4Suppl4/4819.pdf
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