Anti-stress properties of buprenorphine: a better choice for stress-induced relapse to drug addiction

• Main Authors: Ahmad Bidin, Mohammad Ashraf, Rosman, Nurul Nazierah, Suhaimi, Maryam Saadah, Syd Mohmad Faudzi, Syed Mohd Syahmi, Ridzwan, Irna Elina
• 格式: Conference or Workshop Item
• 語言: English
• 出版: 2015
• 主題: RS Pharmacy and materia medica
• 在線閱讀: http://irep.iium.edu.my/44337/1/44337.pdf; http://irep.iium.edu.my/44337/

Compared to methadone, buprenorphine has a unique pharmacological profile in which it is a partial agonist at the mu- and NOP, but antagonist at the kappa-opioid receptors. This gives advantage to buprenorphine to have lesser abusive tendency and has ability to reduce relapse to drug taking. Previou...