In vivo anxiolytic and in vitro anti-inflammatory activities of water-soluble extract (WSE) of Nigella sativa (L.) seeds

• Main Authors: Babar, Z. M., Jaswir, Irwandi, Tareq, A. M., Ali Reza, A. S. M., Azizi, W. M., Mahamad Maifiah, Mohd Hafidz, Ahfter, F., Hasan, M., Farhad, S., Uddin, M. M. Rokib, Ichwan, S. J. A., Ahmed, Qamar Uddin, Bakhtiar, M. Taher, Mawa, I.
• Format: Article
• Language: English
• Published: Taylor and Francis 2019
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/92041/1/92041_In%20vivo%20anxiolytic%20and%20in%20vitro%20anti-inflammatory%20activities.pdf; http://irep.iium.edu.my/92041/; https://www.tandfonline.com/doi/abs/10.1080/14786419.2019.1667348; https://doi.org/10.1080/14786419.2019.1667348

The WSE is a highly polar, gummy and mucilaginous bioactive content of the Nigella sativa (L.) seeds. This study reports the anxiolytic and anti-inflammatory effects of WSE investigated using Elevated Plus Maze (EPM) and Hole-Board Test (HBT) in adult mice and human RBCs haemolysis inhibition and...