Targeting the crosstalk of epigenetic modifications and immune evasion in nasopharyngeal cancer

• Main Authors: Looi, Chin King, Foong, Lian Chee, Chung, Felicia Fei Lei *, Khoo, Alan Soo Beng, Loo, Ee Mun, Leong, Chee Onn, Mai, Chun Wai
• 格式: Article
• 出版: Springer 2023
• 主题: QH Natural history; QR Microbiology; RF Otorhinolaryngology
• 在线阅读: http://eprints.sunway.edu.my/2751/; https://link.springer.com/article/10.1007/s10565-023-09830-9

Nasopharyngeal carcinoma (NPC) is a distinct type of head and neck cancer that is highly associated with Epstein-Barr virus (EBV) infection. EBV acts as an epigenetic driver in NPC tumorigenesis, reprogramming the viral and host epigenomes to regulate viral latent gene expression, and creating an en...