New synthetic phenylquinazoline derivatives induce apoptosis by targeting the pro-survival members of the BCL-2 family
Chemo-resistant cancer cells acquire robust growth potential through cell signaling mechanisms such as the down-regulation of tumor suppressors and the up-regulation of pro-survival proteins, respectively. To overcome chemo-resistance of cancer, small molecule drugs that interact with the cell signa...
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| Main Authors: | , , , , , , |
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| 格式: | Article |
| 出版: |
Elsevier
2022
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| 主题: | |
| 在线阅读: | http://eprints.sunway.edu.my/3113/ https://doi.org/10.1016/j.bmcl.2022.128731 |
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