Elevated Serum Transforming Growth Factor β1 Levels in Epstein-Barr Virus-Associated Diseases and Their Correlation with Virus-Specific Immunoglobulin A (IgA) and IgM

• Main Authors: Xu, Jingwu, Ahmad, Ali, Jones, James F., Dolcetti, Riccardo, Vaccher, Emanuela, Prasad, Umapati, Menezes, José
• Format: Article
• Published: American Society for Microbiology 2000
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/25856/; https://doi.org/10.1128/JVI.74.5.2443-2446.2000

Transforming growth factor β (TGF-β) is an immunosuppressive cytokine which can induce immunoglobulin A (IgA) switch and Epstein-Barr virus (EBV) replication in latently infected cells. Here we report elevated serum levels of TGF-β in various EBV-associated diseases correlating positively with EBV-...