SELEX modifications and bioanalytical techniques for aptamer-target binding characterisation

• 主要な著者: Tan, Sze Y., Amandeep Sidhu, Clarence M. Ongkudon, Michael K. Danquah, Yon, John L. S., Caleb Acquah
• フォーマット: 論文
• 言語: English
• 出版事項: Taylor & Francis 2016
• 主題: QP Physiology
• オンライン･アクセス: https://eprints.ums.edu.my/id/eprint/15484/1/SELEX_modifications_and_bioanalytical_techniques_for_aptamer.pdf; https://eprints.ums.edu.my/id/eprint/15484/; https://dx.doi.org/10.1080/10408347.2016.1157014

The quest to improve the detection of biomolecules and cells in health and life sciences has led to the discovery and characterization of various affinity bioprobes. Libraries of synthetic oligonucleotides (ssDNA/ssRNA) with randomized sequences are employed during Systematic Evolution of Ligands by...