Impact of IsaA gene disruption: decreasing staphylococcal biofilm and alteration of transcriptomic and proteomic profiles

• Main Authors: Ma, Pei Yee, Chong, Chun Wie, Thian, Leslie Lung Than, Sulong, Anita, Ho, Ket Li, Neela, Vasantha Kumari, Sekawi, Zamberi, Liew, Yun Khoon
• 格式: Article
• 出版: Multidisciplinary Digital Publishing Institute 2022
• 在线阅读: http://psasir.upm.edu.my/id/eprint/101793/; https://www.mdpi.com/2076-2607/10/6/1119

Staphylococcus aureus expresses diverse proteins at different stages of growth. The immunodominant staphylococcal antigen A (IsaA) is one of the proteins that is constitutively produced by S. aureus during colonisation and infection. SACOL2584 (or isaA) is the gene that encodes this protein. It has...