The role of TGFβ in human cancers

Transforming growth factor β (TGFβ) is secreted as a large latent precursor from both normal and transformed cells which needs to be activated for biological activity. The active TGFβ binds either directly to TβR-II or indirectly by binding to β-glycan which then presents the TGFβ to TβR-II. Formati...

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Bibliographic Details
Main Authors: Wong, Shew-Fung, Lai, Leslie C.
Format: Article
Language:English
Published: Elsevier 2001
Online Access:http://psasir.upm.edu.my/id/eprint/112551/3/112551.pdf
http://psasir.upm.edu.my/id/eprint/112551/
https://www.sciencedirect.com/science/article/pii/S0031302516346414
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