Candida glabrata gene expression response upon engulfment by THP-1 macrophages
Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata durin...
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المؤلفون الرئيسيون: | , |
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التنسيق: | Conference or Workshop Item |
اللغة: | English |
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2024
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الوصول للمادة أونلاين: | http://psasir.upm.edu.my/id/eprint/115493/1/115493.jpg http://psasir.upm.edu.my/id/eprint/115493/ |
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my.upm.eprints.1154932025-03-06T02:25:48Z http://psasir.upm.edu.my/id/eprint/115493/ Candida glabrata gene expression response upon engulfment by THP-1 macrophages Ismail, Elysha Nur Than, Leslie Thian Lung Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata during macrophage interaction to understand its adaptive strategies against the host immune system, specifically focusing on genes linked to altered metabolism and cell wall modifications. The rise in multidrug-resistant C. globroto strains limits treatment options, necessitating a congrefensive understanding of its gone functions and interactions. 2024 Conference or Workshop Item PeerReviewed image en http://psasir.upm.edu.my/id/eprint/115493/1/115493.jpg Ismail, Elysha Nur and Than, Leslie Thian Lung (2024) Candida glabrata gene expression response upon engulfment by THP-1 macrophages. In: 14th Malaysian Symposium of Biomedical Science 2024, 1-2 Jun. 2024, Universiti Putra Malaysia, Serdang. . (Submitted) |
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Universiti Putra Malaysia |
building |
UPM Library |
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Asia |
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Malaysia |
content_provider |
Universiti Putra Malaysia |
content_source |
UPM Institutional Repository |
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http://psasir.upm.edu.my/ |
language |
English |
description |
Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata during macrophage interaction to understand its adaptive strategies against the host immune system, specifically focusing on genes linked to altered metabolism and cell wall modifications. The rise in multidrug-resistant C. globroto strains limits treatment options, necessitating a congrefensive understanding of its gone functions and interactions. |
format |
Conference or Workshop Item |
author |
Ismail, Elysha Nur Than, Leslie Thian Lung |
spellingShingle |
Ismail, Elysha Nur Than, Leslie Thian Lung Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
author_facet |
Ismail, Elysha Nur Than, Leslie Thian Lung |
author_sort |
Ismail, Elysha Nur |
title |
Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
title_short |
Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
title_full |
Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
title_fullStr |
Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
title_full_unstemmed |
Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
title_sort |
candida glabrata gene expression response upon engulfment by thp-1 macrophages |
publishDate |
2024 |
url |
http://psasir.upm.edu.my/id/eprint/115493/1/115493.jpg http://psasir.upm.edu.my/id/eprint/115493/ |
_version_ |
1825810762314022912 |
score |
13.252575 |