Transcriptomic and proteomic profiling revealed reprogramming of carbon metabolism in acetate-grown human pathogen Candida glabrata

• Main Authors: Chew, Shu Yih, Brown, Alistair J. P., Lau, Benjamin Yii Chung, Cheah, Yoke Kqueen, Ho, Kok Lian, Sandai, Doblin, Yahaya, Hassan, Than, Leslie Thian Lung
• 格式: Article
• 出版: BMC 2021
• 在线阅读: http://psasir.upm.edu.my/id/eprint/93415/; https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-020-00700-8

Background: Emergence of Candida glabrata, which causes potential life-threatening invasive candidiasis, has been widely associated with high morbidity and mortality. In order to cause disease in vivo, a robust and highly efficient metabolic adaptation is crucial for the survival of this fungal path...