Antibody-drug conjugates: the paradigm shifts in the targeted cancer therapy

• Main Authors: Aggarwal, Devesh, Yang, Jie, Salam, Md. Abdus, Sengupta, Sagnik, Al-Amin, Md. Yusuf, Mustafa, Saad, Khan, Mohammad Aasif, Huang, Xun, Pawar, Jogendra Singh
• Format: Article
• Language: English; English
• Published: Frontiers Media S.A. 2023
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://irep.iium.edu.my/106285/7/106285_Antibody-drug%20conjugates.pdf; http://irep.iium.edu.my/106285/13/106285_Antibody-drug%20conjugates_SCOPUS.pdf; http://irep.iium.edu.my/106285/; https://www.frontiersin.org/articles/10.3389/fimmu.2023.1203073/full

Cancer is one of the deadliest diseases, causing million of deaths each year globally. Conventional anti-cancer therapies are non-targeted and have systemic toxicities limiting their versatile applications in many cancers. So, there is an unmet need for more specific therapeutic options that will...