Active targeted ligand-aza-BODIPY conjugate for near-infrared photodynamic therapy in melanoma

• Main Authors: Ng, Shie Yin, Kamkaew, Anyanee, Fu, Nanyan, Kue, Chin Siang, Chung, Lip Yong, Kiew, Lik Voon, Wittayakun, Jatuporn, Burgess, Kevin, Lee, Hong Boon
• 格式: Article
• 出版: Elsevier 2020
• 主題: RM Therapeutics. Pharmacology; RS Pharmacy and materia medica
• 在線閱讀: http://eprints.um.edu.my/37758/

Active targeting compound, a non-iodinated derivative of IK-IK-I-2-azaBODIPY (1a) was previously reported to preferentially bind melanoma over healthy cells. In this study, we evaluate the photodynamic therapy (PDT) efficiency on melanoma cells of 1a, together with its reversed sequence compound KI-...