Development of Halal modified release gliclazide 60 mg tablets by central composite design and production by direct compression

• المؤلفون الرئيسيون: Elsayed, Tarek Mohamed Ali, Mandal, Uttam Kumar, Kasmuri, Abdul Razak
• التنسيق: Conference or Workshop Item
• اللغة: English
• منشور في: 2014
• الموضوعات: RS Pharmacy and materia medica
• الوصول للمادة أونلاين: http://irep.iium.edu.my/38282/1/ICIP_2014.pdf; http://irep.iium.edu.my/38282/; http://www.iium.edu.my/icip2014/download/proceeding.pdf

Background: Gliclazide is a second generation sulphonylurea drug used for the treatment of type 2 diabetes mellitus. Commercially available modified release (MR) gliclazide tablet is a once-daily formulation that employs a hydrophilic matrix of a hypromellose for drug release retardant activity. It...