Filamin A-interacting protein (FILIP) is a region-specific modulator of myosin 2b and controls spine morphology and NMDA receptor accumulation

• Main Authors: Yagi, Hideshi, Nagano, Takashi, Xie, Min-Jue, Ikeda, Hiroshi, Kuroda, Kazuki, Komada, Munekazu, Iguchi, Tokuichi, Rahman, Mohammad Tariqur, Morikubo, Soichi, Noguchi, Koichi, Murase, Kazuyuki, Okabe, Masaru, Sato, Makoto
• 格式: Article
• 語言: English
• 出版: Nature Publishing Group 2014
• 主題: QP Physiology
• 在線閱讀: http://irep.iium.edu.my/38350/1/Tariqur.pdf; http://irep.iium.edu.my/38350/; http://www.nature.com/srep/2014/140815/srep06353/full/srep06353.html#affil-auth

Learning and memory depend on morphological and functional changes to neural spines. Non-muscle myosin 2b regulates actin dynamics downstream of long-term potentiation induction. However, the mechanism by which myosin 2b is regulated in the spine has not been fully elucidated. Here, we show that...