Amplification of homo sapiens CYP2B6 gene using polymerase chain reaction (PCR) for cloning and expression / Norfahmi Mohd Yusof

• 主要作者: Mohd Yusof, Norfahmi
• 格式: Thesis
• 語言: English
• 出版: 2008
• 主題: Pharmaceutical chemistry
• 在線閱讀: https://ir.uitm.edu.my/id/eprint/103988/1/103988.PDF; https://ir.uitm.edu.my/id/eprint/103988/

CYP2B6 is a member of cytochrome P450 group of enzymes. The protein encoded by the CYP2B6 gene is the primary metabolizer of a number of drug substrates, such as buprion, cyclosphosphamide, ifosfamide, pethidine, efavirenz, neverapine, ketamine and propofol. In this study, amplification of CYP2B6 ge...