Cell Cycle Arrest and Apoptosis Induction via Modulation of Mitochondrial Integrity by Bcl-2 Family Members and Caspase Dependence in Dracaena cinnabari-Treated H400 Human Oral Squamous Cell Carcinoma

• 主要な著者: Alabsi, A.M., Lim, K.L., Paterson, I.C., Ali-Saeed, R., Muharram, B.A.
• フォーマット: 論文
• 言語: English
• 出版事項: Hindawi Publishing Corporation 2016
• 主題: R Medicine; RK Dentistry
• オンライン･アクセス: http://eprints.um.edu.my/17483/1/AlabsiAM_%282016%29.pdf; http://eprints.um.edu.my/17483/; http://dx.doi.org/10.1155/2016/4904016

Dracaena cinnabari Balf.f. is a red resin endemic to Socotra Island, Yemen. Although there have been several reports on its therapeutic properties, information on its cytotoxicity and anticancer effects is very limited. This study utilized a bioassay-guided fractionation approach to determine the cy...