Survival and Intra-Nuclear Trafficking of Burkholderia pseudomallei: Strategies of Evasion from Immune Surveillance?

• Main Authors: Vadivelu, Jamuna, Vellasamy, Kumutha Malar, Thimma, Jaikumar, Mariappan, Vanitha, Kang, Wen Tyng, Choh, Leang Chung, Shankar, Esaki Muthu, Wong, Kum Thong
• Format: Article
• Published: Public Library of Science 2017
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/22859/; https://doi.org/10.1371/journal.pntd.0005241

Background: During infection, successful bacterial clearance is achieved via the host immune system acting in conjunction with appropriate antibiotic therapy. However, it still remains a tip of the iceberg as to where persistent pathogens namely, Burkholderia pseudomallei (B. pseudomallei) reside/hi...