The role of Isocitrate Lyase (ICL1) in the metabolic adaptation of Candida albicans biofilms

• المؤلفون الرئيسيون: Ishola, Oluwaseun Ayodeji, Seng, Yeat Ting, Tabana, Yasser M., Ahmed, Mowaffaq Adam, Yunus, Muhammad Amir, Mohamed, Rafeezul, Leslie, Thian Lung Than, Sandai, Doblin
• التنسيق: مقال
• اللغة: English
• منشور في: Ahvaz Jundishapur University of Medical Sciences 2016
• الوصول للمادة أونلاين: http://psasir.upm.edu.my/id/eprint/53088/1/The%20role%20of%20Isocitrate%20Lyase%20%28ICL1%29%20in%20the%20metabolic%20adaptation%20of%20Candida%20albicans%20biofilms.pdf; http://psasir.upm.edu.my/id/eprint/53088/; http://jjm.ajums.ac.ir

Background A major characteristic of Candida biofilm cells that differentiates them from free-floating cells is their high tolerance to antifungal drugs. This high resistance is attributed to particular biofilm properties, including the accumulation of extrapolymeric substances, morphogenetic switc...