Effects of Nicotine Administration and Nicotine Cessation on Bone Histomorphometry and Bone Biomarkers in Sprague–Dawley Male Rats

• 主要な著者: Hapidin, Hermizi, Othman, Faizah, Soelaiman, Ima-Nirwana, Shuid, Ahmad Nazrun, Mohamed, Norazlina
• フォーマット: 論文
• 出版事項: 2011
• 主題: RA0421 Public health. Hygiene. Preventive Medicine
• オンライン･アクセス: http://eprints.usm.my/35760/; https://doi.org/10.1007/s00223-010-9426-4

Nicotine is a major alkaloid of tobacco, which can increase free radical formation, leading to osteoporosis. The effects of nicotine administration and cessation on bone histomorphometry and biomarkers were studied in 28 Sprague–Dawley male rats. Rats aged 3 months and weighing 250–300 g were d...